In this section we address the most common forms of allergy to medications, knowing that other reactions are not described in the topic.
1. HIVES
Urticaria is characterized by rash of welts variable size and location, with an evolution of 24-48 hours. In most cases is associated with angioedema (angioneurotic edema or Quincke), instead of causing itching sensation of weight or tension, and deformation of the face.
Medications that cause allergic urticaria:
ACTH. Acetylsalicylic acid. Aminoglycosides. Amoxicillin. Local anesthetics (FOR group). Anovulatory. Tricyclic antidepressants. Barbiturates. Benzodiazepines. Bleomycin. Calcitonin. Captopril. Carbamazepine. Cephalosporins. Cyclophosphamide. Cis-platinum. Clindamycin. Clonidine. Chloramphenicol. Iodinated contrast. Daunorubicin. Coumadin. Diphenylhydantoin. Digital. Dipyrone. Mercurial diuretics. Doxorubicin. Ergotamine. Streptodornase. Streptokinase. Ethambutol. Etilclorovinol. Ethosuximide. Ethylenediamine. Phenothiazines. Heparin. Chloral hydrate. Indomethacin. Insulin. Isoniazid. L-asparaginase. Levamisole. Meprobamate. Methaqualone. Metoclopramide. Metronidazole. Miconazole. Naproxen. Nitrofurantoin. Penicillins. Pentazocine. Piperazine. Polymyxin B. Procainamide. Procarbazine. Propylthiouracil. Propranolol. Quinidine. Quinine. Ranitidine. Rifampicin. Whole blood. Sera. Sulfonamides. Tetraciclinas.Tiabendazol.Tiazidas. Tragacanth. TSH. Vaccines. Vancomicina.Vitamina B12.
2. ANAPHYLAXIS
It is a general reaction of the organism after contact, application or taking medication, which appears immediately (5-10 minutes) in the form of itching in the palms and soles, general heat, rash skin whealing, thick tongue sensation and some difficulty swallowing, difficulty breathing, coughing, wheezing and fatigue, tachycardia, vomiting, bowel movements, anxiety.
If after this table is persistent and does not see a purple coloration of the lips and skin, nails, hypotension and cardiac arrhythmia, and entry into shock, with loss of consciousness and exitus.
The incidence of anaphylaxis (allergic shock) is known in relation to penicillin from 10 to 50 per 100,000 injections, and these are fatal reactions 100 to 500 per year in USA.
Drugs that cause anaphylaxis:
ACTH. Acetylsalicylic acid. Aminoglycosides. Amoxicillin. Local anesthetics (FOR group). Anovulatory. Tricyclic antidepressants. Barbiturates. Benzodiazepines. Bleomycin. Calcitonin. Captopril. Carbamazepine. Cephalosporins. Cyclophosphamide. Cis-platinum. Clindamycin. Clonidine. Chloramphenicol. Iodinated contrast. Daunorubicin. Coumadin. Diphenylhydantoin. Digital. Dipyrone. Mercurial diuretics. Doxorubicin. Ergotamine. Streptodornase. Streptokinase. Ethambutol. Etilclorovinol. Ethosuximide. Ethylenediamine. Phenothiazines. Heparin. Chloral hydrate. Indomethacin. Insulin. Isoniazid. L-asparaginase. Levamisole. Meprobamate. Methaqualone. Metoclopramide. Metronidazole. Miconazole. Naproxen. Nitrofurantoin. Penicillins. Pentazocine. Piperazine. Polymyxin B. Procainamide. Procarbazine. Propylthiouracil. Propranolol. Quinidine. Quinine. Ranitidine. Rifampicin. Whole blood. Sera. Sulfamidas.Tetraciclinas.Tiabendazol.Tiazidas. Tragacanth. TSH. Vaccines. Vancomycin. Vitamin B12
3. Vesicular exanthema BULLOUS
3.1. ERYTHEMA MULTIFORME
It is a skin reaction with injuries to his home are simple or pink macules or erythematous papules, sometimes urticarial appearance, usually in its central region evolve to that level by taking an aspect edematous and therefore high pitch dark purple and even look Pemphigoid with persistent peripheral edge erythematosus (rosette or target lesions).
There may be itching or burning sensation associated, and is characteristic of this dermatosis symmetric lesion distribution.
The causes are various, sometimes appears as a symptom of infection or activation of certain microorganisms (herpes simplex, mycoplasma, bacteria) and other mechanisms are for drug allergies.
Drugs that produce or multiform erythema multiforme:
Allopurinol NSAIDs. (NSAIDs): acetylsalicylic acid, phenylbutazone, ibuprofen, meclofenamate, piroxicam, sulindac, zomepirac. Barbiturates. Benzodiazepines. Busulfan. Carbamazepine. Cephalosporins. Cimetidine. Clindamycin. Chloroquine. Chlorpropamide. Codeine. Diphenylhydantoin. Erythromycin. Streptomycin. Estrogen. Ethambutol. Ethosuximide. Phenothiazines. Phenolphthalein. Furosemide. Glutethimide. Griseofulvin. Hydralazine. Isoniazid. Ketoconazole. Mechlorethamine. Methotrexate. Miconazole. Minoxidil. Nitrogen mustards. Nalidixic acid. D-penicillamine. Penicillins. Prazosin. Propylthiouracil. Propranolol. Kinins.
3.2. Toxic epidermal necrolysis (Lyell’s syndrome)
It is a reaction in the form of generalized erythema, formation of large blisters (like burns), epidermal detachment and high mortality.
Drugs that can produce are:
or sulfonamides
or pyrazolones
or hydantoins
or penicillin
Tags: allergy, allergy to medications, dermatosis symmetric, Drug Allergies, Drugs, medications
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